Motif ID: SOX{8,9,10}.p2

Z-value: 1.488


Transcription factors associated with SOX{8,9,10}.p2:

Gene SymbolEntrez IDGene Name
SOX10 6663 SRY (sex determining region Y)-box 10
SOX8 30812 SRY (sex determining region Y)-box 8
SOX9 6662 SRY (sex determining region Y)-box 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX9chr17_+_701171770.381.1e-08Click!
SOX10chr22_-_383805380.212.0e-03Click!


Activity profile for motif SOX{8,9,10}.p2.

activity profile for motif SOX{8,9,10}.p2


Sorted Z-values histogram for motif SOX{8,9,10}.p2

Sorted Z-values for motif SOX{8,9,10}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX{8,9,10}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_103989195 40.647 NM_001823
CKB
creatine kinase, brain
chr14_-_103989112 40.053 CKB
creatine kinase, brain
chr6_-_128841432 30.126 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr3_-_149688886 27.767 PFN2
profilin 2
chr1_-_26232890 27.246 NM_001145454
NM_005563
STMN1

stathmin 1

chr18_-_74729049 24.832 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr18_-_74728963 24.498 MBP
myelin basic protein
chr2_-_175869910 24.059 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr12_+_120933911 23.698 DYNLL1
dynein, light chain, LC8-type 1
chr19_+_36359346 21.756 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr1_-_85930610 21.245 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_-_26232643 20.675 NM_203401
STMN1
stathmin 1
chr1_+_151032866 19.575 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr8_+_26435339 19.039 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr1_+_151032880 18.881 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr5_+_140739589 18.730 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr15_+_52311408 18.709 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr12_+_120933832 18.314 NM_001037495
NM_003746
DYNLL1

dynein, light chain, LC8-type 1

chr3_+_39509069 17.746 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr15_+_52311438 17.697 MAPK6
mitogen-activated protein kinase 6
chr2_+_149633173 17.265


chr16_+_89988416 16.528 NM_001197181
TUBB3
tubulin, beta 3 class III
chr15_-_83876769 16.517 HDGFRP3
hepatoma-derived growth factor, related protein 3
chr5_+_74632992 16.511 NM_000859
NM_001130996
HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

chr1_+_50571963 16.348 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_-_46867840 16.291 NM_001008938
NM_014756
CKAP5

cytoskeleton associated protein 5

chr12_+_120933916 16.260 DYNLL1
dynein, light chain, LC8-type 1
chr3_-_149688638 16.202 NM_002628
NM_053024
PFN2

profilin 2

chr9_+_80911990 16.048 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr15_+_52311432 15.819 MAPK6
mitogen-activated protein kinase 6
chr17_-_1248346 15.487 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr1_+_151032683 15.290 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_-_156399183 14.699 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr3_-_185826748 14.523 NM_004454
ETV5
ets variant 5
chr6_-_46293404 14.374 RCAN2
regulator of calcineurin 2
chr2_-_55277592 14.159 RTN4
reticulon 4
chr15_-_83876165 13.923 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr4_-_176733901 13.742 GPM6A
glycoprotein M6A
chr5_+_74633043 13.707 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr2_-_55277421 13.657 RTN4
reticulon 4
chr10_+_102106771 13.519 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr2_-_55277672 13.427 RTN4
reticulon 4
chr12_-_49582296 13.352 TUBA1A
tubulin, alpha 1a
chr2_-_2334887 13.294 NM_015025
MYT1L
myelin transcription factor 1-like
chrX_-_13835187 13.105 GPM6B
glycoprotein M6B
chr2_-_55277653 13.096 RTN4
reticulon 4
chr2_-_55277459 13.077 RTN4
reticulon 4
chr2_-_55277620 13.035 RTN4
reticulon 4
chr2_-_55277698 12.800 NM_020532
NM_153828
NM_207520
RTN4


reticulon 4


chr15_+_80696569 12.774 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr3_+_111717585 12.680 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr1_-_55352893 12.656 DHCR24
24-dehydrocholesterol reductase
chr17_-_37764165 12.491 NM_006160
NEUROD2
neurogenic differentiation 2
chr8_-_101965554 12.408 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chrX_-_13835313 12.290 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr16_+_58534045 12.119 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr6_+_114178516 11.942 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr8_-_101965601 11.938 NM_003406
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_-_95392449 11.925 CNN3
calponin 3, acidic
chr11_+_60691911 11.899 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr1_-_32801606 11.685 NM_023009
MARCKSL1
MARCKS-like 1
chr10_+_70748476 11.639 NM_015634
KIAA1279
KIAA1279
chr6_-_79944397 11.632 NM_001201362
NM_001201363
NM_004242
NM_138730
HMGN3



high mobility group nucleosomal binding domain 3



chr1_-_95392501 11.626 NM_001839
CNN3
calponin 3, acidic
chr16_+_15528324 11.414 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr1_-_55352920 11.381 NM_014762
DHCR24
24-dehydrocholesterol reductase
chr4_+_41614911 11.350 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr7_-_121036320 11.331 FAM3C
family with sequence similarity 3, member C
chr8_-_101965096 11.313 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr17_-_73150493 11.206 HN1
hematological and neurological expressed 1
chr7_-_111846384 11.185 NM_014705
DOCK4
dedicator of cytokinesis 4
chr1_+_155294217 11.136 NM_014328
RUSC1
RUN and SH3 domain containing 1
chr12_-_49582800 10.918 NM_006009
TUBA1A
tubulin, alpha 1a
chr21_+_41239346 10.905 NM_006198
PCP4
Purkinje cell protein 4
chr8_-_27115935 10.888 STMN4
stathmin-like 4
chr5_-_16936371 10.866 NM_012334
MYO10
myosin X
chrX_+_102611379 10.850 NM_001006612
NM_001006613
NM_001006614
NM_016303
WBP5



WW domain binding protein 5



chr1_-_26233367 10.848 NM_203399
STMN1
stathmin 1
chr6_-_79944324 10.818 HMGN3
high mobility group nucleosomal binding domain 3
chr5_+_140797243 10.759 NM_018927
PCDHGB7
protocadherin gamma subfamily B, 7
chr1_-_55352818 10.662 DHCR24
24-dehydrocholesterol reductase
chrX_-_13835012 10.536 GPM6B
glycoprotein M6B
chr5_-_78809658 10.384 NM_004272
HOMER1
homer homolog 1 (Drosophila)
chr1_+_156589085 10.313 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr6_-_3227776 10.252 NM_178012
TUBB2B
tubulin, beta 2B class IIb
chr1_+_155293727 10.228 NM_001105205
RUSC1
RUN and SH3 domain containing 1
chr8_-_101965194 10.221 NM_001135699
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr6_+_30688085 10.023 TUBB
tubulin, beta class I
chrX_-_13835213 9.972 GPM6B
glycoprotein M6B
chr11_-_61584228 9.916 FADS1
fatty acid desaturase 1
chr2_-_151344145 9.910 NM_005168
RND3
Rho family GTPase 3
chr5_+_140729723 9.885 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr12_+_49212253 9.882 NM_000725
NM_001206915
CACNB3

calcium channel, voltage-dependent, beta 3 subunit

chr15_-_72523713 9.790 NM_001206796
NM_001206797
NM_001206798
NM_002654
NM_182470
NM_182471
PKM2





pyruvate kinase, muscle





chr2_-_132121730 9.785 NM_001077637
WTH3DI
RAB6C-like
chr1_-_55352881 9.654 DHCR24
24-dehydrocholesterol reductase
chr11_-_122932806 9.587 HSPA8
heat shock 70kDa protein 8
chr20_-_50384899 9.544 NM_006045
ATP9A
ATPase, class II, type 9A
chr11_-_72380107 9.513 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr2_+_130737234 9.504 NM_032144
RAB6C
RAB6C, member RAS oncogene family
chr7_+_73703704 9.412 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr8_-_27115897 9.251 NM_030795
STMN4
stathmin-like 4
chr5_+_140797270 9.215 PCDHGB7
protocadherin gamma subfamily B, 7
chr20_-_50384861 9.214 ATP9A
ATPase, class II, type 9A
chr7_-_121036355 9.076 NM_001040020
NM_014888
FAM3C

family with sequence similarity 3, member C

chr12_-_45269953 9.059 NELL2
NEL-like 2 (chicken)
chr8_-_110693233 9.055 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr14_+_103800534 9.031 EIF5
eukaryotic translation initiation factor 5
chr13_+_42846255 9.030 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr12_-_45270157 8.998 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr12_-_45270071 8.950 NELL2
NEL-like 2 (chicken)
chr4_+_154125589 8.918 NM_015271
TRIM2
tripartite motif containing 2
chr10_+_121578768 8.836 NM_001243194
INPP5F
inositol polyphosphate-5-phosphatase F
chr7_+_153584383 8.830 NM_001039350
DPP6
dipeptidyl-peptidase 6
chr18_-_21891469 8.774 NM_001242508
OSBPL1A
oxysterol binding protein-like 1A
chr3_-_52567809 8.767 NT5DC2
5'-nucleotidase domain containing 2
chr15_+_84115979 8.747 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr19_-_47551881 8.658 NM_017854
TMEM160
transmembrane protein 160
chr16_-_19533285 8.503 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chr11_-_122932844 8.465 NM_006597
NM_153201
HSPA8

heat shock 70kDa protein 8

chr19_+_47104389 8.395 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chrX_+_21958714 8.385 NM_004595
SMS
spermine synthase
chr11_+_63953630 8.293 STIP1
stress-induced-phosphoprotein 1
chr7_+_128379428 8.258 CALU
calumenin
chr6_+_123100645 8.208 NM_001446
FABP7
fatty acid binding protein 7, brain
chr7_+_128379452 8.186 CALU
calumenin
chr17_-_9940004 8.150 NM_201432
GAS7
growth arrest-specific 7
chr7_+_128379400 8.143 CALU
calumenin
chr3_-_52567708 8.141 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr5_-_146435589 8.100 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr4_-_87028805 8.093 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr20_+_30193083 7.983 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr5_-_43313581 7.924 NM_001098272
NM_002130
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr7_+_128379395 7.708 CALU
calumenin
chr3_+_111718006 7.700 NM_001008273
TAGLN3
transgelin 3
chr18_-_55289014 7.627 NARS
asparaginyl-tRNA synthetase
chr2_+_159313466 7.605 NM_001005476
NM_003628
PKP4

plakophilin 4

chr8_+_109455874 7.575 TTC35
tetratricopeptide repeat domain 35
chr17_-_39684585 7.558 NM_002276
KRT19
keratin 19
chr6_+_121756744 7.533 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr18_-_55288951 7.483 NARS
asparaginyl-tRNA synthetase
chr7_+_5632453 7.455 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr5_+_140213968 7.427 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr4_+_156680125 7.398 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr17_-_39684499 7.376 KRT19
keratin 19
chr1_+_36621751 7.367 NM_018067
MAP7D1
MAP7 domain containing 1
chr1_-_243418675 7.363 NM_001042404
NM_001042405
NM_014812
CEP170


centrosomal protein 170kDa


chrM_+_4770 7.330


chr7_+_129710336 7.330 NM_014997
KLHDC10
kelch domain containing 10
chr7_-_131241321 7.292 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr16_+_8768403 7.198 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr19_+_52693229 7.188 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr11_-_66115016 6.995 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr1_-_153643417 6.992 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_+_200708604 6.941 NM_203459
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr11_+_63953666 6.935 STIP1
stress-induced-phosphoprotein 1
chr17_-_1303402 6.930 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr1_-_197115566 6.896 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr20_+_17207669 6.857 PCSK2
proprotein convertase subtilisin/kexin type 2
chr16_-_74808474 6.774 FA2H
fatty acid 2-hydroxylase
chr1_-_94702916 6.770 ARHGAP29
Rho GTPase activating protein 29
chr1_+_36023389 6.730 NM_001014839
NM_001014841
NM_014284
NCDN


neurochondrin


chr10_-_126107454 6.716 OAT
ornithine aminotransferase
chr1_-_153643474 6.714 NM_004515
ILF2
interleukin enhancer binding factor 2, 45kDa
chr7_+_129710401 6.698 KLHDC10
kelch domain containing 10
chr22_-_50523737 6.682 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_-_153643433 6.674 ILF2
interleukin enhancer binding factor 2, 45kDa
chr4_+_83351725 6.665 NM_021204
ENOPH1
enolase-phosphatase 1
chr7_-_44887697 6.642 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr16_+_22524843 6.641 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr16_-_74808699 6.611 NM_024306
FA2H
fatty acid 2-hydroxylase
chr8_+_82192717 6.577 NM_001444
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr2_-_61765345 6.577 XPO1
exportin 1 (CRM1 homolog, yeast)
chr2_-_61765367 6.567 XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_-_246580710 6.549 NM_022743
SMYD3
SET and MYND domain containing 3
chr1_-_153643428 6.545 ILF2
interleukin enhancer binding factor 2, 45kDa
chr11_+_63953586 6.505 NM_006819
STIP1
stress-induced-phosphoprotein 1
chr18_-_55289026 6.488 NM_004539
NARS
asparaginyl-tRNA synthetase
chr4_-_5890142 6.412 CRMP1
collapsin response mediator protein 1
chr22_-_50523780 6.382 NM_139202
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr10_-_123356158 6.346 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr16_+_6069094 6.330 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr19_-_55919324 6.321 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr17_+_40610899 6.205 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr7_+_149570004 6.202 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr22_-_50523853 6.195 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_+_83072922 6.162 NM_006670
TPBG
trophoblast glycoprotein
chr4_+_41614933 6.155 LIMCH1
LIM and calponin homology domains 1
chr7_+_5632435 6.132 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr5_-_43313492 6.106 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr19_+_45394459 6.094 NM_001128916
NM_001128917
NM_006114
TOMM40


translocase of outer mitochondrial membrane 40 homolog (yeast)


chr6_-_116575170 6.091 NM_021648
TSPYL4
TSPY-like 4
chr4_-_176733413 6.047 GPM6A
glycoprotein M6A
chr4_-_5894695 6.042 NM_001014809
CRMP1
collapsin response mediator protein 1
chr11_+_57479994 6.019 NM_001144012
NM_015959
TMX2

thioredoxin-related transmembrane protein 2

chr3_-_52001388 6.015 NM_020418
NM_001174100
NM_033008
PCBP4


poly(rC) binding protein 4


chr19_+_52693334 5.986 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr4_+_83351765 5.977 ENOPH1
enolase-phosphatase 1
chr1_-_201476248 5.977 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chrX_-_77225134 5.974 NM_001029891
PGAM4
phosphoglycerate mutase family member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 6.09e-21 GO:0009987 cellular process
1.97 2.39e-14 GO:0007399 nervous system development
1.54 2.13e-11 GO:0048856 anatomical structure development
1.47 1.31e-10 GO:0032502 developmental process
1.49 2.43e-10 GO:0007275 multicellular organismal development
1.55 3.50e-10 GO:0048731 system development
1.46 5.01e-09 GO:0071840 cellular component organization or biogenesis
1.46 8.07e-09 GO:0016043 cellular component organization
1.53 4.44e-08 GO:0071842 cellular component organization at cellular level
1.51 5.41e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.87 5.14e-06 GO:0022008 neurogenesis
1.88 1.10e-05 GO:0048699 generation of neurons
1.37 1.76e-05 GO:0051179 localization
1.77 2.71e-05 GO:0007049 cell cycle
1.33 2.97e-05 GO:0051716 cellular response to stimulus
2.26 3.49e-05 GO:0007409 axonogenesis
1.19 4.82e-05 GO:0065007 biological regulation
1.34 6.38e-05 GO:0023052 signaling
2.02 7.93e-05 GO:0000278 mitotic cell cycle
2.19 8.67e-05 GO:0048812 neuron projection morphogenesis
1.81 1.11e-04 GO:0040011 locomotion
2.18 1.19e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.37 1.52e-04 GO:0007411 axon guidance
2.09 1.85e-04 GO:0031175 neuron projection development
1.21 2.20e-04 GO:0050794 regulation of cellular process
1.81 2.40e-04 GO:0051128 regulation of cellular component organization
1.99 2.46e-04 GO:0048666 neuron development
2.03 4.63e-04 GO:0032990 cell part morphogenesis
1.25 4.90e-04 GO:0032501 multicellular organismal process
2.02 7.90e-04 GO:0048858 cell projection morphogenesis
2.16 8.78e-04 GO:0007264 small GTPase mediated signal transduction
1.19 9.09e-04 GO:0050789 regulation of biological process
1.51 1.26e-03 GO:0006996 organelle organization
1.82 1.47e-03 GO:0030182 neuron differentiation
1.21 1.94e-03 GO:0044237 cellular metabolic process
1.77 2.92e-03 GO:0071844 cellular component assembly at cellular level
1.96 3.21e-03 GO:0000904 cell morphogenesis involved in differentiation
1.31 3.98e-03 GO:0007165 signal transduction
1.72 4.05e-03 GO:0022402 cell cycle process
1.82 4.72e-03 GO:0030030 cell projection organization
1.93 5.52e-03 GO:0007417 central nervous system development
1.70 6.32e-03 GO:0033554 cellular response to stress
1.90 8.19e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.30 9.02e-03 GO:0006807 nitrogen compound metabolic process
2.97 1.49e-02 GO:0007265 Ras protein signal transduction
1.74 1.53e-02 GO:0022403 cell cycle phase
1.31 1.58e-02 GO:0051234 establishment of localization
1.39 1.65e-02 GO:0048869 cellular developmental process
3.54 1.90e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.39 1.91e-02 GO:0030154 cell differentiation
1.51 2.21e-02 GO:0051641 cellular localization
1.31 2.49e-02 GO:0006810 transport
1.50 2.49e-02 GO:0033036 macromolecule localization
2.12 2.86e-02 GO:0051329 interphase of mitotic cell cycle
1.29 3.02e-02 GO:0034641 cellular nitrogen compound metabolic process
1.48 3.26e-02 GO:0035556 intracellular signal transduction
1.77 3.56e-02 GO:0000902 cell morphogenesis
1.35 3.80e-02 GO:0042221 response to chemical stimulus
2.09 4.26e-02 GO:0051325 interphase
2.29 4.30e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.73 4.58e-02 GO:0032989 cellular component morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 5.13e-24 GO:0005737 cytoplasm
1.20 8.40e-18 GO:0044424 intracellular part
1.18 2.76e-16 GO:0005622 intracellular
1.35 6.03e-13 GO:0044444 cytoplasmic part
1.66 5.85e-11 GO:0005829 cytosol
1.31 7.28e-09 GO:0044422 organelle part
1.30 1.80e-08 GO:0044446 intracellular organelle part
1.48 3.86e-08 GO:0043228 non-membrane-bounded organelle
1.48 3.86e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.17 2.24e-07 GO:0043226 organelle
1.17 2.27e-07 GO:0043229 intracellular organelle
1.63 7.73e-07 GO:0005856 cytoskeleton
1.16 6.60e-05 GO:0043231 intracellular membrane-bounded organelle
1.16 7.97e-05 GO:0043227 membrane-bounded organelle
1.83 2.01e-04 GO:0015630 microtubule cytoskeleton
1.05 1.68e-03 GO:0044464 cell part
1.05 1.73e-03 GO:0005623 cell
1.79 1.96e-03 GO:0030054 cell junction
2.52 2.28e-03 GO:0005819 spindle
1.35 4.31e-03 GO:0043233 organelle lumen
1.36 5.13e-03 GO:0044428 nuclear part
1.35 5.19e-03 GO:0031974 membrane-enclosed lumen
1.34 9.59e-03 GO:0070013 intracellular organelle lumen
1.29 1.11e-02 GO:0043234 protein complex
1.25 1.27e-02 GO:0032991 macromolecular complex
2.38 1.36e-02 GO:0030424 axon
1.50 1.93e-02 GO:0044430 cytoskeletal part
1.18 2.15e-02 GO:0005634 nucleus
4.84 2.40e-02 GO:0032432 actin filament bundle
1.85 2.42e-02 GO:0043005 neuron projection
1.83 3.28e-02 GO:0045202 synapse
2.90 4.33e-02 GO:0042470 melanosome
2.90 4.33e-02 GO:0048770 pigment granule
1.35 4.37e-02 GO:0031981 nuclear lumen
1.72 4.46e-02 GO:0005730 nucleolus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.33 1.13e-16 GO:0005515 protein binding
1.16 1.79e-12 GO:0005488 binding
1.39 7.14e-04 GO:0000166 nucleotide binding
1.88 1.06e-03 GO:0008092 cytoskeletal protein binding
2.00 1.64e-02 GO:0003779 actin binding
1.37 2.71e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.35 3.68e-02 GO:0017076 purine nucleotide binding
1.35 4.12e-02 GO:0032553 ribonucleotide binding
1.35 4.12e-02 GO:0032555 purine ribonucleotide binding